It is completely possible for one station to be missing while many other stations work normally.
A TV antenna system does not receive all stations as one combined broadcast. Each station transmits on a particular RF channel, from a particular transmitter location, at a particular power level, and under its own propagation conditions.
A missing station may:
Broadcast from a different tower location.
Use a different RF frequency band.
Arrive at your location with a weaker predicted signal.
Be affected by terrain or obstructions differently.
Experience interference on its particular RF frequency.
Fall outside the strongest reception area of a directional antenna.
Be temporarily operating at reduced power or experiencing a broadcast issue.
The virtual channel number displayed on the television can also be misleading. For example, a station displayed as Channel 5.1 does not necessarily broadcast on RF channel 5.
The Channel Master TV Antenna Map & Technical Information Tool can show the actual RF channel, tower location, direction, distance, and predicted signal strength for stations available at your address.
Comparing the missing station with the stations you receive successfully can often reveal why that particular channel is more difficult to receive.